Inositol phosphates: Profusion and confusion

SnapShot: Inositol Phosphates

Inositol phosphates in aquatic systems

While there is a considerable body of research on the abundance and behavior of inositol hexakisphosphate in soils, much less is known regarding its behaviour in aquatic systems. The observed physico-chemical behaviour of this organic P species suggests that in marine and freshwaters, it should be complexed and precipitated by major ions such as calcium, magnesium, iron or aluminium, and thus i...

Stereoselective synthesis of inositol phosphates

Pseudomonas putia'a oxidation of benzene affords cis-3,5-cyclohexadiene1,2diol (JJ which serves as a novel precursor for the syntheses of several natural products including (+)-pinitol, (+)-condunto1 F, D-(-)-myo-inositol 1,4,5-trisphosphate and Dmyo-inositol 1-phosphate. The versatility of this approach is further demonstrated by the preparation of other functionalised cyclitol derivatives, in...

The metabolism and function of inositol phosphates.

& Numa, S . (1984) Nature (London) 307, 604608 Olsen, R. W. (1981) J . Neurochem. 37, 1-13 Parker, I . , Sumikawa, K . & Miledi, R. (1985) f roc . R . Soc. London Ser. B 225, 99 ~ 106 Sakmann, B., Methfessel, C., Mishina, M., Takahashi, T., Takai, T., Kurasaki, M., Fukuda, K . & Numa, S . (1985) Nature (London) 382, 538-543 Sigel, E., Stephenson, F. A,, Mamalaki, C. & Barnard, E. A. (1982) J . ...

Effects of inositol starvation on the levels of inositol phosphates and inositol lipids in Neurospora crassa.

An inositol-requiring strain of Neurospora crassa was labelled during growth in liquid medium with [3H]inositol, and the levels of inositol phosphates and phosphoinositides were determined under inositol-sufficient and inositol-starved conditions. Because the mutant has an absolute requirement for inositol, the total mass of inositol-containing compounds could be determined. Inositol-containing...